Diastolic myocardial function indexes in patients with obstructive sleep apnea
Abstract
To study diastolic myocardial function pulsed wave Doppler tissue (PWDT) echocardiography was recorded in 102 patients with obstructive sleep apnea syndrome. The left ventricular diastolic dysfunction has been identified in patients with moderate and severe obstructive sleep apnea syndrome. Changes in diastolic profile manifest as a decrease of the speed of early diastolic wave peak speed increases late diastolic wave peak and, as a consequence, reduction in the ratio of peak velocities increase time of isovolumic relaxation and time of delay of left ventricular early diastolic filling, as well as reducing Em / Am indicators, Em (mean septal and lateral) of the mitral valve less than 9 cm/s. The revealed changes increase with increasing severity of the disease. At the same time indicators of tissue left ventricular diastolic dysfunction in patients with obstructive sleep apnea syndrome appear on the stage of the disease, when the global left ventricular diastolic function has virtually broken. Diastolic dysfunction of the mitral valve has been identified in patients with normal transmitral flow. Tissue Doppler echocardiography can be used for early diagnosis of the left ventricular diastolic dysfunction.
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10. Mooe T., Franklin K.A., Wiklund U., et al. Sleep-Disordered Breathing and Myocardial Ischemia in Patients With Coronary Artery Disease // Chest. – 2000. – Vol. 117. – P. 1597-1602.
11. Ponikowski P., Voors A.A, Anker S.D., et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. // Eur Heart J. – 2016. – Vol. 37. – P. 2129-2200.
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2. Анкудинов А.С., Калягин А.Н., Колбасеева О.В. Галектин-3 и предсердный натрийуретический пептид: диагностические и прогностические возможности у больных, страдающих хронической сердечной недостаточностью и остеоартрозом коленных суставов // Сибирский медицинский журнал (Иркутск). – 2015. – № 136(5). – С. 43-46.
3. Бузунов Р.В., Легейда И.В., Царева Е.В. Храп и синдром обструктивного апноэ сна у взрослых и детей: Практическое руководство для врачей. – М., 2013. – 124 с.
4. Калинкина Т.В., Ларева Н.В., Чистякова М.В. Современные методы диагностики диастолической дисфункции левого желудочка у больных гипертонической болезнью // Забайкальский медицинский вестник. – 2016. – №2. – С. 115-120. – URL: http://chitgma.ru/zmv2/journal/2016/2/18.pdf.
5. Мареев В.Ю., Агеев Ф.Т., Арутюнов Г.П. и др. Национальные рекомендации ОССН, РКО и РНМОТ по диагностике и лечению хронической сердечной недостаточности (четвертый пересмотр) // Журнал сердечная недостаточность. – 2013. – Т. 14. №7. – С. 379-472.
6. Свиряев Ю.В., Коростовцева Л.С., Звартау Н.Э. Прогностическое значение синдрома обструктивного апноэ во сне: промежуточные результаты пятилетнего проспективного наблюдения // Артериальная гипертензия. – 2011. – Т. 17. №1. – С. 10-16.
7. Чазова И.Е., Литвин А.Ю. Синдром обструктивного апноэ сна и связанные с ним сердечно-сосудистые осложнения // Медицина критических состояний. – 2010. – № 1. – С. 3-10.
8. Щекотов В.В., Янкина Т.И., Жижилев Е.В. Структурно-функциональные особенности сердца у больных с синдромом обструктивного апноэ сна в зависимости от степени его тяжести и выраженности метаболического синдрома // Клиницист. – 2011. - №1. – С. 28-32.
9. Calvin A.D., Albuquerque A.D., Adachi T., Somers V.K. Obstructive Sleep Apnea and Heart Failure. // Curr Treat Opt Cardiovasс Med. – 2009. – Vol. 11. – P. 447-454.
10. Mooe T., Franklin K.A., Wiklund U., et al. Sleep-Disordered Breathing and Myocardial Ischemia in Patients With Coronary Artery Disease // Chest. – 2000. – Vol. 117. – P. 1597-1602.
11. Ponikowski P., Voors A.A, Anker S.D., et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. // Eur Heart J. – 2016. – Vol. 37. – P. 2129-2200.
12. Somers V.K., White D.P., Amin R., et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. // J Am Coll Cardiol. – 2008. – Vol. 52. – P. 686-717.
REFERENCES
1. Alekhin M. Tissue Doppler in clinical echocardiography. – Moscow, 2006. - 104 p. (in Russian)
2. Ankudinov A.S., Kalyagin A.N., Kolbaseeva O.V. Galectin-3 and atrial natriuretic peptide: diagnostic and prognostic capabilities in patients with chronic heart failure and osteoarthritis of the knee joints. // Sibirskij Medicinskij Zurnal (Irkutsk). – 2015. – Vol. 136 (5). – P. 43-46. (in Russian)
3. Buzunov R., Legeyda I., Tsareva E. Snoring and obstructive sleep apnea syndrome in adults and children. A practical guide for physicians. – Moscow, 2013. – 124 p. (in Russian)
4. Kalinkina T.V., Lareva N.V., Chystyakova M.V. Modern methods of left ventricular diastolic dysfunction diagnosis in patients with essential hypertension. // Zabaykal'skiy Meditsinskiy Vestnik. – 2016. - №2. – P. 115-120. – URL: http://chitgma.ru/zmv2/journal/2016/2/18.pdf. (in Russian)
5. Mareev V., Ageev F., Arutyunov G. et al. National guidelines OSSN, RKO and RNMOT for diagnosis and treatment of chronic heart failure (fourth revision). // Zhurnal serdechnaja nedostatochnost'. – 2013. – Vol. 14. №7. – P. 379-472. (in Russian)
6. Sviryaev Y., Korostovtseva L., Zvartau N. Prognostic significance of obstructive sleep apnea: intermediate results of a five-year prospective study. // Arterial'naja gipertenzija. – 2011. – Vol. 17. №1. – P. 10-16. (in Russian)
7. Chazova I., Litvin A. Obstructive sleep apnea syndrome and its associated cardiovascular complications. // Medicina kriticheskih sostoyanii. – 2010. - №1. – P. 3-10. (in Russian)
8. Shchekotov V., Yankina T., Zhizhilev E. Structural and functional characteristics of the heart in patients with obstructive sleep apnea syndrome, depending on its severity and severity of metabolic syndrome. // Klinitsist. – 2011. - №1. – P. 28-32. (in Russian)
9. Calvin A.D., Albuquerque A.D., Adachi T., Somers V.K. Obstructive Sleep Apnea and Heart Failure. // Curr Treat Opt Cardiovasс Med. – 2009. – Vol. 11. – P. 447-454.
10. Mooe T., Franklin K.A., Wiklund U., et al. Sleep-Disordered Breathing and Myocardial Ischemia in Patients With Coronary Artery Disease // Chest. – 2000. – Vol. 117. – P. 1597-1602.
11. Ponikowski P., Voors A.A, Anker S.D., et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. // Eur Heart J. – 2016. – Vol. 37. – P. 2129-2200.
12. Somers V.K., White D.P., Amin R., et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. // J Am Coll Cardiol. – 2008. – Vol. 52. – P. 686-717.
Published
2018-04-03
How to Cite
КАРАСЕВА, Наталья Викторовна; ГОНЧАРОВА, Елена Валерьевна.
Diastolic myocardial function indexes in patients with obstructive sleep apnea.
Sibirskij Medicinskij Zurnal (Irkutsk) = Siberian Medical Journal (Irkutsk) 16+, [S.l.], v. 145, n. 6, p. 12-15, apr. 2018.
ISSN 1815-7572. Available at: <http://smj.ismu.baikal.ru/index.php/osn/article/view/106>. Date accessed: 01 jan. 2026.
Issue
Section
Original research
