Change in diffusion ability of lungs and its correction in younghypertensive patients with stable angina
Abstract
The aim of investigation was the analysis of alveolar diffusion in young hypertensive patients with stable angina. The investigation included 136 patients and 30 healthy people. The patients received 3 therapy programs. The changes in the process of alveolar diffusion (DLCO), which were the consequences of complex cardio-respiratory abnormalitie, were established. Standard therapy did not influence the value of DLCO. Inclusions of complex program sessions of interval normobaric hypoxytherapy promoted the improvement of the process of transalveolar diffusion. Standard hypoxytherapy with liposomal drugs promoted increase in alveolar diffusion and made the value of DLCO closer to indices of healthy people.
References
1. Белялов Ф.И. Лечение внутренних болезней в условиях коморбидности. – Иркутск РИО ИГМАПО, 2012. – 283 с.
2. Бугаенко В.В. Гендерные особенности диагностики, течения и лечения ишемической болезни сердца // Рациональная фармакотерапия. – 2015. - № 1. – С. 5-19.
3. Поликутина О.М., Слепынина Ю.С., Кацюба М.В., Каретникова В.Н. Диффузионная способность легких как прогностический маркер у пациентов с сердечной недостаточностью // Сибирский медицинский журнал (Томск). – 2012. – Т. 27. № 2. – С. 29-34.
4. Леонова М.В. Новые лекарственные формы и системы доставки лекарственных средств: особенности пероральных лекарственных форм. Часть 2 // Лечебное дело. – 2009. - №3. – С. 18-26.
5. Серебровская Т.В., Шатило В.Б. Опыт использования интервальной гипоксии для предупреждения и лечения заболеваний сердечно-сосудистой системы // Кровообращение и гемостаз. – 2014. - №1-2. – С. 13-33.
6. Levchenko T.S., Hartner W.C., Verma D.D. et al. ATP-loaded liposomes for targeted treatment in models of myocardial ischemia // Methods Mol. Biol. – 2010. – Vol. 605. – P. 361-375.
7. Liu M., M. Li, Wang G. et al. Heart-targeted nanoscale drug delivery systems // J. Biomed. Nanotechnol. – 2014. – Vol. 10 (9). – P. 2038-2062.
8. Levchenko T.S., William D., Hartner W.C., Torchilin V.P. Liposomes in diagnosis and treatment of cardiovascular disorders // Debakey Cardiovasc. J. – 2012. – Vol. 8(1). – Р. 36-41.
REFERENCES
1. Belyalov F.I. Treatment internal diseases in comorbidity conditions. – Irkutsk: RIO IGMAPO, 2012. – 283 p. (in Russian)
2. Bugaenko V.V. Gender features of diagnostic, clinical course and treatment of ischemic heart disease // Ratsionalnaya farmakoterapia. – 2015. – N 1. – P. 5-19. (in Russian)
3. Polikutina O.M., Slepinina U.S., Kocuba V.N. diffusing capacity of the lung for CO how prognosis marker on patients with heart failure // Sibirskij Meditsinskij Zhurnal (Tomsk). – 2012. – Vol. 27 (2). – P. 29-34. (in Russian)
4. Leonova M.V. New pharmaceutical dosage form and systems delivery pharmaceutical means. Part 2 // Lechebnoe delo. – 2009. - №3. – P. 18-26. (in Russian)
5. Serebrovskaya T.V., Shatilo V.B. Experience of use interval hypoxia for prevention and treatment cardiovascular diseases system // Krovoobraschenie I Gimostaz. – 2014. - №1-2. – P. 13-33. (in Russian)
6. Levchenko T.S., Hartner W.C., Verma D.D., et al. ATP-loaded liposomes for targeted treatment in models of myocardial ischemia // Methods Mol. Biol. – 2010. – Vol. 605. – P. 361-375.
7. Liu M., M. Li, Wang G. et al. Heart-targeted nanoscale drug delivery systems // J. Biomed. Nanotechnol. – 2014. – Vol. 10 (9). – P. 2038-2062.
8. Levchenko T.S., William D., Hartner W.C., Torchilin V.P. Liposomes in diagnosis and treatment of cardiovascular disorders // Debakey Cardiovasc. J. – 2012. – Vol. 8 (1). – Р. 36-41.
2. Бугаенко В.В. Гендерные особенности диагностики, течения и лечения ишемической болезни сердца // Рациональная фармакотерапия. – 2015. - № 1. – С. 5-19.
3. Поликутина О.М., Слепынина Ю.С., Кацюба М.В., Каретникова В.Н. Диффузионная способность легких как прогностический маркер у пациентов с сердечной недостаточностью // Сибирский медицинский журнал (Томск). – 2012. – Т. 27. № 2. – С. 29-34.
4. Леонова М.В. Новые лекарственные формы и системы доставки лекарственных средств: особенности пероральных лекарственных форм. Часть 2 // Лечебное дело. – 2009. - №3. – С. 18-26.
5. Серебровская Т.В., Шатило В.Б. Опыт использования интервальной гипоксии для предупреждения и лечения заболеваний сердечно-сосудистой системы // Кровообращение и гемостаз. – 2014. - №1-2. – С. 13-33.
6. Levchenko T.S., Hartner W.C., Verma D.D. et al. ATP-loaded liposomes for targeted treatment in models of myocardial ischemia // Methods Mol. Biol. – 2010. – Vol. 605. – P. 361-375.
7. Liu M., M. Li, Wang G. et al. Heart-targeted nanoscale drug delivery systems // J. Biomed. Nanotechnol. – 2014. – Vol. 10 (9). – P. 2038-2062.
8. Levchenko T.S., William D., Hartner W.C., Torchilin V.P. Liposomes in diagnosis and treatment of cardiovascular disorders // Debakey Cardiovasc. J. – 2012. – Vol. 8(1). – Р. 36-41.
REFERENCES
1. Belyalov F.I. Treatment internal diseases in comorbidity conditions. – Irkutsk: RIO IGMAPO, 2012. – 283 p. (in Russian)
2. Bugaenko V.V. Gender features of diagnostic, clinical course and treatment of ischemic heart disease // Ratsionalnaya farmakoterapia. – 2015. – N 1. – P. 5-19. (in Russian)
3. Polikutina O.M., Slepinina U.S., Kocuba V.N. diffusing capacity of the lung for CO how prognosis marker on patients with heart failure // Sibirskij Meditsinskij Zhurnal (Tomsk). – 2012. – Vol. 27 (2). – P. 29-34. (in Russian)
4. Leonova M.V. New pharmaceutical dosage form and systems delivery pharmaceutical means. Part 2 // Lechebnoe delo. – 2009. - №3. – P. 18-26. (in Russian)
5. Serebrovskaya T.V., Shatilo V.B. Experience of use interval hypoxia for prevention and treatment cardiovascular diseases system // Krovoobraschenie I Gimostaz. – 2014. - №1-2. – P. 13-33. (in Russian)
6. Levchenko T.S., Hartner W.C., Verma D.D., et al. ATP-loaded liposomes for targeted treatment in models of myocardial ischemia // Methods Mol. Biol. – 2010. – Vol. 605. – P. 361-375.
7. Liu M., M. Li, Wang G. et al. Heart-targeted nanoscale drug delivery systems // J. Biomed. Nanotechnol. – 2014. – Vol. 10 (9). – P. 2038-2062.
8. Levchenko T.S., William D., Hartner W.C., Torchilin V.P. Liposomes in diagnosis and treatment of cardiovascular disorders // Debakey Cardiovasc. J. – 2012. – Vol. 8 (1). – Р. 36-41.
Published
2018-04-09
How to Cite
МУХИН, Игорь Витальевич; ГАВРИЛЯК, Валентина Геннадьевна.
Change in diffusion ability of lungs and its correction in younghypertensive patients with stable angina.
Sibirskij Medicinskij Zurnal (Irkutsk) = Siberian Medical Journal (Irkutsk) 16+, [S.l.], v. 143, n. 4, p. 13-16, apr. 2018.
ISSN 1815-7572. Available at: <http://smj.ismu.baikal.ru/index.php/osn/article/view/127>. Date accessed: 01 jan. 2026.
Issue
Section
Original research
