CHRONIC APPENDICITIS – MORPHOLOGICAL DIAGNOSIS

  • Ирина Александровна Шурыгина Irkutsk Scientific Centre of Surgery and Traumatology http://orcid.org/0000-0003-3980-050X
  • Наталья Николаевна Дрёмина Irkutsk Scientific Centre of Surgery and Traumatology http://orcid.org/0000-0002-2540-4525
  • Александр Иосифович Панасюк Irkutsk State Medical University; Irkutsk Regional Order "Badge of Honor" Clinical Hospital
  • Олег Витославович Каня Irkutsk Scientific Centre of Surgery and Traumatology; Irkutsk Regional Pathoanatomical Bureau
  • Михаил Геннадьевич Шурыгин Irkutsk Scientific Centre of Surgery and Traumatology

Abstract

Objective: to develop a standard for the description of histological preparations for chronic appendicitis. Material and methods: The object of the study was the intraoperative material of 49 patients with chronic appendicitis. For comparison, intraoperative samples of patients operated for various appendicular pathologies were studied: in 12 cases – acute phlegmonous appendicitis, in two – acute gangrenous, in one case – lymphocytic hyperplasia of the mucosa of the appendix. Six intact appendices served as controls. A fixation of a sample of appendix tissue was made, the preparation of histological preparations, their staining by two methods – with hematoxylin-eosin and by the method of Van Gieson. The description of the preparations was carried out according to the scheme developed by the authors, a score of changes was made. Results: A method has been developed that makes it possible to differentiate chronic appendicitis from other disorders of the appendix. Diagnostic criteria for chronic appendicitis include a change in the shape of the lumen of the appendix (p<0.01), the absence of neutrophil infiltration or its weak expression (p < 0.01), mucosal atrophy and subatrophy (p<0.01), sclerotic changes in the appendix wall (p<0.01), lipomatosis (p<0.01), atrophy of the muscular membrane (p<0.01). With a score of more than 5 points, chronic appendicitis is diagnosed.

References

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9. Crabbe M.M., Norwood S.H., Robertson H.D., Silva J.S. Recurrent and chronic appendicitis// Surg Gynecol Obstet. 1986. Vol. 163. N 1. P. 11-13.
10. Ferlitsch A., Puespoek A., Gasche C. Endoscopic imaging of the vermiform appendix (with video)// Gastrointest. Endosc. 2014. Vol. 80, N 6. P. 1156-1160. DOI: 10.1016/j.gie.2014.07.048.
11. Izbicki J.R., Knoefel W.T., Wilker D.K. Accurate diagnosis of acute appendicitis: a retrospective and prospective analysis of 686 patients// Eur. J. Surg. 1992. Vol. 158, N 4. P. 227-231.
12. Hawes A.S., Whalen G.F. Recurrent and chronic appendicitis: the other inflammatory conditions of the appendix// Am Surg. 1994. Vol. 60. N 3. P. 217-219.
13. Mysorekar V.V., Chanda S., Dandeka C.P. Mast cells in surgically resected appendices// Indian J. Pathol. Microbiol. 2006. Vol. 49. N 2. P. 229-233.
14. Putzki H., Reichert B. Evaluating histologic findings after appendectomy// Zentralbl Chir. 1991. Vol. 116. N 4. P. 261-265.
Published
2019-01-20
How to Cite
ШУРЫГИНА, Ирина Александровна et al. CHRONIC APPENDICITIS – MORPHOLOGICAL DIAGNOSIS. Sibirskij Medicinskij Zurnal (Irkutsk) = Siberian Medical Journal (Irkutsk) 16+, [S.l.], v. 153, n. 2, p. 17-19, jan. 2019. ISSN 1815-7572. Available at: <http://smj.ismu.baikal.ru/index.php/osn/article/view/289>. Date accessed: 17 feb. 2026.
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Vol 153 No 2 (2018)
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