SEROLOGICAL MONITORING OF CYTOMEGAL VIRAL INFECTION IN ADULTS IN BAKU
Abstract
Aim: of investigation was to carry out the serological monitoring of cytomegalovirus infection in adults for detecting the clinical form.
Methods. The 104 patients with cytomegaloviral infection have been observed for the serological markers of CMVinfection. The middle age of patients was 31,4±1,4 years. For detecting of the serological markers of cytomegalovirus infection (anti-CMV IgG and anti-CMV IgM antibodies) the ELISA method have been used.
Result. Acute (active) CMVI in women was detected in the age group up to 30 years (6.5%), in men - in the group of 50 years and older (40.0%). In women and men, cytomegalovirus infection mainly proceeded as a chronic infection and the detection rate was 81.8% and 81.6%, respectively. In men, acute (active) CMVI was established almost 3 times more often than in women (18.4% vs. 6.1%).
Conclusion. On the basis of results of serological monitoring the clinical forms of cytomegalovirus infection in adults have been determined.
References
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REFERENCES
1. Dolgikh T.I., Dalmatov V.V., Zapary N.S., Kadtsyna T.V. Cytomegalovirus infection in Omsk region // Zhurnalmikrobiologii, epidemiologii i immunobiologii. 2008. №3. P.85-87.(in Russian)
2. Zhukova L.I., Kovalevskaya O.L., Lebedev V.V., Gorodin V.N. Acquired overt cytomegalovirus infection in immunocompetent adult patients // Epidemiologiya i infektsionnyyebolezni. 2014. №1. P.11-16. (in Russian)
3. Petrova K.K. Causes and diagnostic of miscarriage in early pregnancy in women with cytomegalovirus infection // Byulleten’ fiziologii i patologiidykhaniya. 2017. Is. 64. P.50-54. DOI: 10.12737/article_59360bd64c0640.82215175 (in Russian)
4. Bechtel M., Frout W. Sexually transmitted diseases // Clin. Obstetr. Gynecol. 2015. Vol. 48. №1. P.172-184. 5. Berth M., Grangeot-Keros L., Heskia F., et al. Analytical issues possibly affecting the performance of commersial human cytomegalovirus IgG avidity assays // Eur. J. Clin. Microbiol. Infect. Dis. 2014. Vol. 33. №9. P.1579-1584.
6. Leruez-Ville M., Selier Y., Salomon L., et al. Prediction of fetal infection in cases with cytomegalovirus immunoglobulin M in the first trimestr of pregnancy: a retrospective cohort // Clin. Infect. Dis. 2013. Vol. 56. №10. P.1428-1435.
7. Lumley S., Patel M., Griffiths P. The combination of specific IgM antibodies and IgG antibodies of low avidity does not always indicate primary infection with cytomegalovirus // J. Med. Virol. 2014. Vol. 86. №5. P.834-837.
8. LuviraV., Chamnanchanunt S., Bussaratid V., et al. Seroprevalence of latent cytomegalovirus infection among elderly Thais // Southeast Asian J. Trop. Med. Publ. Hlth. 2012. Vol. 43. №6. P.1419-1425.
9. Rahbar A., Orrego A., Peredo I., et al. Human cytomegalovirus infection levels in glioblastomamultiforme are of prognostic value for survival // J. Clin. Virol. 2013. Vol. 57. №1. P.36-42.
10. Susan P., Ricardo P., Erica M., et al. Cytomegalovirus in pregnancy: to screen or not to screen // BMC Pregnancy / Сhildbirth. 2013. Vol. 13. P.96.
11. Tomastik T., Lawilinska B., Rawlik D., et al. Congenital cytomegaly in one twin – a case report // Med. WiekuRozwoj. 2012. Vol. 6. №3. P.252-260.
12. Wu D., Wu Y., Wang L., et al. Evaluation of a novel array based toxoplasma, rubella, cytomegalovirus and herpes simplex virus IgG enzyme linked immunosorbent assay and its comparison with virionserion enzyme linked immunosorbent assays // Ann. Lab. Med. 2014. Vol. 34. №1. P.38-42.
2. Жукова Л.И., Ковалевская О.И., Лебедев В.В., Городин В.Н. Приобретенная острая манифестная цитомегаловирусная инфекция у иммуносохранных взрослых больных // Эпидемиология и инфекционные болезни. 2014. №1. С.11-16.
3. Петрова К.К. Причина и диагностика раннего невынашивания при цитомегаловирусной инфекции // Бюллетень физиологии и патологии дыхания. 2017. Вып. 64. С.50-54. DOI: 10.12737/article_59360bd64c0640.82215175
4. Bechtel M., Frout W. Sexually transmitted diseases // Clin. Obstetr. Gynecol. 2015. Vol. 48. №1. P.172-184.
5. Berth M., Grangeot-Keros L., Heskia F., et al. Analytical issues possibly affecting the performance of commersial human cytomegalovirus IgG avidity assays // Eur. J. Clin. Microbiol. Infect. Dis. 2014. Vol. 33. №9. P.1579-1584.
6. Leruez-Ville M., Selier Y., Salomon L., et al. Prediction of fetal infection in cases with cytomegalovirus immunoglobulin M in the first trimestr of pregnancy: a retrospective cohort // Clin. Infect. Dis. 2013. Vol. 56. №10. P.1428-1435.
7. Lumley S., Patel M., Griffiths P. The combination of specific IgM antibodies and IgG antibodies of low avidity does not always indicate primary infection with cytomegalovirus // J. Med. Virol. 2014. Vol. 86. №5. P.834-837.
8. LuviraV., Chamnanchanunt S., Bussaratid V., et al. Seroprevalence of latent cytomegalovirus infection among elderly Thais // Southeast Asian J. Trop. Med. Publ. Hlth. 2012. Vol. 43. №6. P.1419-1425.
9. Rahbar A., Orrego A., Peredo I., et al. Human cytomegalovirus infection levels in glioblastomamultiforme are of prognostic value for survival // J. Clin. Virol. 2013. Vol. 57. №1. P.36-42.
10. Susan P., Ricardo P., Erica M., et al. Cytomegalovirus in pregnancy: to screen or not to screen // BMC Pregnancy / Сhildbirth. 2013. Vol. 13. P.96.
11. Tomastik T., Lawilinska B., Rawlik D., et al. Congenital cytomegaly in one twin – a case report // Med. WiekuRozwoj. 2012. Vol. 6. №3. P.252-260.
12. Wu D., Wu Y., Wang L., et al. Evaluation of a novel array based toxoplasma, rubella, cytomegalovirus and herpes simplex virus IgG enzyme linked immunosorbent assay and its comparison with virionserion enzyme linked immunosorbent assays // Ann. Lab. Med. 2014. Vol. 34. №1. P.38-42.
REFERENCES
1. Dolgikh T.I., Dalmatov V.V., Zapary N.S., Kadtsyna T.V. Cytomegalovirus infection in Omsk region // Zhurnalmikrobiologii, epidemiologii i immunobiologii. 2008. №3. P.85-87.(in Russian)
2. Zhukova L.I., Kovalevskaya O.L., Lebedev V.V., Gorodin V.N. Acquired overt cytomegalovirus infection in immunocompetent adult patients // Epidemiologiya i infektsionnyyebolezni. 2014. №1. P.11-16. (in Russian)
3. Petrova K.K. Causes and diagnostic of miscarriage in early pregnancy in women with cytomegalovirus infection // Byulleten’ fiziologii i patologiidykhaniya. 2017. Is. 64. P.50-54. DOI: 10.12737/article_59360bd64c0640.82215175 (in Russian)
4. Bechtel M., Frout W. Sexually transmitted diseases // Clin. Obstetr. Gynecol. 2015. Vol. 48. №1. P.172-184. 5. Berth M., Grangeot-Keros L., Heskia F., et al. Analytical issues possibly affecting the performance of commersial human cytomegalovirus IgG avidity assays // Eur. J. Clin. Microbiol. Infect. Dis. 2014. Vol. 33. №9. P.1579-1584.
6. Leruez-Ville M., Selier Y., Salomon L., et al. Prediction of fetal infection in cases with cytomegalovirus immunoglobulin M in the first trimestr of pregnancy: a retrospective cohort // Clin. Infect. Dis. 2013. Vol. 56. №10. P.1428-1435.
7. Lumley S., Patel M., Griffiths P. The combination of specific IgM antibodies and IgG antibodies of low avidity does not always indicate primary infection with cytomegalovirus // J. Med. Virol. 2014. Vol. 86. №5. P.834-837.
8. LuviraV., Chamnanchanunt S., Bussaratid V., et al. Seroprevalence of latent cytomegalovirus infection among elderly Thais // Southeast Asian J. Trop. Med. Publ. Hlth. 2012. Vol. 43. №6. P.1419-1425.
9. Rahbar A., Orrego A., Peredo I., et al. Human cytomegalovirus infection levels in glioblastomamultiforme are of prognostic value for survival // J. Clin. Virol. 2013. Vol. 57. №1. P.36-42.
10. Susan P., Ricardo P., Erica M., et al. Cytomegalovirus in pregnancy: to screen or not to screen // BMC Pregnancy / Сhildbirth. 2013. Vol. 13. P.96.
11. Tomastik T., Lawilinska B., Rawlik D., et al. Congenital cytomegaly in one twin – a case report // Med. WiekuRozwoj. 2012. Vol. 6. №3. P.252-260.
12. Wu D., Wu Y., Wang L., et al. Evaluation of a novel array based toxoplasma, rubella, cytomegalovirus and herpes simplex virus IgG enzyme linked immunosorbent assay and its comparison with virionserion enzyme linked immunosorbent assays // Ann. Lab. Med. 2014. Vol. 34. №1. P.38-42.
Published
2019-12-07
How to Cite
ГУСЕЙНОВА, Замина Ниязи кызы.
SEROLOGICAL MONITORING OF CYTOMEGAL VIRAL INFECTION IN ADULTS IN BAKU.
Sibirskij Medicinskij Zurnal (Irkutsk) = Siberian Medical Journal (Irkutsk) 16+, [S.l.], v. 157, n. 2, p. 45-47, dec. 2019.
ISSN 1815-7572. Available at: <http://smj.ismu.baikal.ru/index.php/osn/article/view/374>. Date accessed: 01 jan. 2026.
Issue
Section
Lifestyle, ecology
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