The valuation of microcirculatory and metabolicdisorders in the patients with vibration disease
Abstract
The article presents the research data of quantitative parameters of microcirculation and metabolism of endogenous biologically active substances in the skin of hands of the patients with vibration disease based on laser Doppler flowmetry and fluorescence spectroscopy. There were revealed microcirculatory disorders of different types and degrees:1) spastic type - 45,2%; 2) normal circulatory type - 34,0%; 3) hyperemic type - 20,8%. A normal circulatory type was characterized by a minimal microcirculatory disorder associated with a greater degree of impairment in the regulation mechanisms. Spastic and hyperemic types were based on multidirectional changes in microcirculation of moderate and severe degrees. In the group of spastic type the accumulation of porphyrins and respiratory enzymes in the skin of hands was revealed due to chronic hypoxia.
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