Quality of life in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease
Abstract
The aim of our work was to evaluate the quality of the life of patients with chronic rhinosinusitis (CRS) associated with gastroesophageal reflux disease (GERD). The authors surveyed 140 people aged from 18 to 81 years with difficulty in nasal breathing of various etiologies and 30 healthy persons using the questionnaire SF-36. The presence of concomitant GERD in patients with CRS (26 patients) leads to a greater reduction in the quality of life in relation to the implementation of physical activity (PH=37±17), to an underestimation of the patient’s health, to the deterioration of the emotional state, stronger than suffering the psychological component (MH=36±9) of health compared to patients with CRS without GERD (29 patients; PН=44±10; MH=43±10). This suggests a causal relationship between GERD and CRS, to allocate a separate nosological form - CRS associated with GERD. Patients with CRS and GERD, have lower rates of mental and physical health, compared with patients with GERD who have no pathology of a nose and paranasal sinuses (28 patients; PН=39±6 и MH=38±11). All patients with CRS associated with GERD have quality of life lower, than in 27 patients with deformation of septi nasi only (PН=56±6 и MH=55±8): there are depressive and anxious feelings, mental distress, decrease in mental and physical health component. Violation of nasal breathing, as a result of inflammation of paranasal sinuses reduces the quality of life more than the violation of nasal breathing noninflammatory genesis of both physical and psychological components of health.
References
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REFERENCES
1. Grigorieva I.N., Romanova T.I. Methodological aspects of the study of quality of life in modern medicine // Clinical and epidemiological problems ethnoecological and digestive diseases. – Krasnoyarsk, 2005. – P. 364–371. (in Russian)
2. Land V.D. Contact health to quality of life in diseases of the nose and paranasal sinuses// Rossiajskaja Rhinologya. –2003. – № 3. – P. 26- 30. (in Russian)
3. Lopatin A.S., Gamow V.P. Acute and chronic rhinosinusitis: etiology, pathogenesis. The clinic, diagnosis and treatment guidelines: Tutorial. – Moscow: Meditsinskoe Informatsionnoe Agentstvo, 2011. – P. 53-57. (in Russian)
4. Palchikov M.A., Shiryaev O.U., Lebedev E.A. Analysis of personality traits of patients with inflammatory diseases of the paranasal sinuses // Nauchno-Meditsinskij Vestnik Tsentralnogo Chernozemia. –2009. –№ 35. – P. 150-154. (in Russian)
5. Piskunov G.Z., Kosyakov S.Y., Starostina E.G. Quality of life in otorhinolaryngology is an urgent need to improve the quality of treatment // Rossiajskaja Rhinologya. – 2002. – №2. – P. 18-19. (in Russian)
6. Bhattacharyya N. Clinical and symptom criteria for the accurate diagnosis of chronic rhinosinusitis // Laryngoscope. – 2006. – Vol. 116. № 7. – Р. 1-22.
7. Dean B.B., Crawley J.A., Schmitt C.M. The burden of illness of gastroesophageal reflux disease: impact on work productivity // Aliment. Pharmacol. Ther. – 2003. – Vol. 17. – P. 1309–1317.
8. DelGaudio J.M. Direct nasopharyngeal reflux of gastric acid is a contributing factor in refractory chronic rhinosinusitis // Laryngoscope. –2005. – Vol. 115. № 6. – P. 946-957.
9. Dibaise J.K., Sharma J.K. Does gastroesophageal reflux contribute to the development of chronic sinusitis? A review of the evidence // Dis. Esophagus. –2006. – Vol.19 – P. 419-424.
10. Dobhan R., Castell D.Normal and abnormal proximal esophageal acid exposure: results of ambulatory dual-probe pH monitoring // Am. J. Gastroenterol. –1993. – Vol.88. №1 – P. 25-29.
11. El-Serag H., Sweet S., Winchester С.Update on the epidemiology of gastroesophageal reflux disease: a systematic review // Gut. – 2013. – Vol. 63– P. 871–880.
12. Fokkens W.J., Lund V.J., Mullol J. European position paper on rhinosinusitis and nasal polyps 2012 // Rhinol. Suppl. – 2012. – Vol. 3. – Р. 1–298.
13. Jenkinson C. Short form 36 (SF-36) health survey questionnaire: normative data for adults of working age // Wright. Br. Med. J. – 1993. – Vol. 306. – P. 1437–1440.
14. Katle E.J., Hart Н., Kjaergaard Т. Nose-and sinus-related quality of life and GERD // Eur. Arch. Otorhiolaringol. – 2012. –Vol. 269. № 1. –P.121–125.
15. Vakil N., Van Zanten S.V., Kahrilas Р., Jones R. Global Consensus Group the Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterol. – 2006. –Vol. 101. №8. –P.1900-1920.
16. Wasan A., Fernandez Е., N. Jamison R., Bhattacharyya N.Association of anxiety and depression with reported disease severity in patients undergoing evaluation for chronic rhinosinusitis // Ann. Otol. Rhinol. Laryngol. – 2007. –Vol. 116. №7. –P. 491-497.
17. Wiklund I.K., Junghard O., Grace E. Quality of life in the reflux and dyspepsia patients. Psychometric documentation of a new disease-specific questionnaire (QOLRAD) // Europ. J. Surg. – 1998. – Vol. 583. – P. 41–49.
2. Ланд В.Д. Связь здоровья с качеством жизни при заболеваниях носа и околоносовых пазух // Российская ринология. – 2003. – № 3. – С. 26– 30.
3. Лопатин А.С., Гамов В.П. Острый и хронический риносинусит: этиология, патогенез. Клиника, диагностика и принципы лечения: Учебное пособие. – М.: Медицинское информационное агентство, 2011. – С. 53– 57.
4. Пальчиков М.А., Ширяев О.Ю., Лебедева Е.А. Анализ особенностей личности пациентов с воспалительными заболеваниями придаточных пазух носа // Научно-медицинский вестник Центрального Черноземья. –2009. –№35. – С. 150-154.
5. Пискунов Г.З., Косяков С. Я., Старостина Е.Г. Исследование качества жизни в оториноларингологии насущная необходимость для повышения качества лечения // Российская ринология. – 2002. – № 2. – С. 18-19.
6. Bhattacharyya N. Clinical and symptom criteria for the accurate diagnosis of chronic rhinosinusitis // Laryngoscope. – 2006. – Vol. 116. № 7. – Р. 1-22.
7. Dean B.B., Crawley J.A., Schmitt C.M. The burden of illness of gastroesophageal reflux disease: impact on work productivity // Aliment. Pharmacol. Ther. – 2003. – Vol. 17. – P. 1309–1317.
8. DelGaudio J.M. Direct nasopharyngeal reflux of gastric acid is a contributing factor in refractory chronic rhinosinusitis // Laryngoscope. –2005. – Vol. 115. № 6. – P. 946-957.
9. Dibaise J.K., Sharma J.K. Does gastroesophageal reflux contribute to the development of chronic sinusitis? A review of the evidence // Dis. Esophagus. –2006. – Vol.19 – P. 419-424.
10. Dobhan R., Castell D.Normal and abnormal proximal esophageal acid exposure: results of ambulatory dual-probe pH monitoring // Am. J. Gastroenterol. –1993. – Vol.88. №1 – P. 25-29.
11. El-Serag H., Sweet S., Winchester С.Update on the epidemiology of gastroesophageal reflux disease: a systematic review // Gut. – 2013. – Vol. 63– P. 871–880.
12. Fokkens W.J., Lund V.J., Mullol J. European position paper on rhinosinusitis and nasal polyps 2012 // Rhinol. Suppl. – 2012. – Vol. 3. – Р. 1–298.
13. Jenkinson C. Short form 36 (SF-36) health survey questionnaire: normative data for adults of working age // Wright. Br. Med. J. – 1993. – Vol. 306. – P. 1437–1440.
14. Katle E.J., Hart Н., Kjaergaard Т. Nose-and sinus-related quality of life and GERD // Eur. Arch. Otorhiolaringol. – 2012. –Vol. 269. № 1. –P.121–125.
15. Vakil N., Van Zanten S.V., Kahrilas Р., Jones R. Global Consensus Group the Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterol. – 2006. –Vol. 101. №8. –P.1900-1920.
16. Wasan A., Fernandez Е., N. Jamison R., Bhattacharyya N.Association of anxiety and depression with reported disease severity in patients undergoing evaluation for chronic rhinosinusitis // Ann. Otol. Rhinol. Laryngol. – 2007. –Vol. 116. №7. –P. 491-497.
17. Wiklund I.K., Junghard O., Grace E. Quality of life in the reflux and dyspepsia patients. Psychometric documentation of a new disease-specific questionnaire (QOLRAD) // Europ. J. Surg. – 1998. – Vol. 583. – P. 41–49.
REFERENCES
1. Grigorieva I.N., Romanova T.I. Methodological aspects of the study of quality of life in modern medicine // Clinical and epidemiological problems ethnoecological and digestive diseases. – Krasnoyarsk, 2005. – P. 364–371. (in Russian)
2. Land V.D. Contact health to quality of life in diseases of the nose and paranasal sinuses// Rossiajskaja Rhinologya. –2003. – № 3. – P. 26- 30. (in Russian)
3. Lopatin A.S., Gamow V.P. Acute and chronic rhinosinusitis: etiology, pathogenesis. The clinic, diagnosis and treatment guidelines: Tutorial. – Moscow: Meditsinskoe Informatsionnoe Agentstvo, 2011. – P. 53-57. (in Russian)
4. Palchikov M.A., Shiryaev O.U., Lebedev E.A. Analysis of personality traits of patients with inflammatory diseases of the paranasal sinuses // Nauchno-Meditsinskij Vestnik Tsentralnogo Chernozemia. –2009. –№ 35. – P. 150-154. (in Russian)
5. Piskunov G.Z., Kosyakov S.Y., Starostina E.G. Quality of life in otorhinolaryngology is an urgent need to improve the quality of treatment // Rossiajskaja Rhinologya. – 2002. – №2. – P. 18-19. (in Russian)
6. Bhattacharyya N. Clinical and symptom criteria for the accurate diagnosis of chronic rhinosinusitis // Laryngoscope. – 2006. – Vol. 116. № 7. – Р. 1-22.
7. Dean B.B., Crawley J.A., Schmitt C.M. The burden of illness of gastroesophageal reflux disease: impact on work productivity // Aliment. Pharmacol. Ther. – 2003. – Vol. 17. – P. 1309–1317.
8. DelGaudio J.M. Direct nasopharyngeal reflux of gastric acid is a contributing factor in refractory chronic rhinosinusitis // Laryngoscope. –2005. – Vol. 115. № 6. – P. 946-957.
9. Dibaise J.K., Sharma J.K. Does gastroesophageal reflux contribute to the development of chronic sinusitis? A review of the evidence // Dis. Esophagus. –2006. – Vol.19 – P. 419-424.
10. Dobhan R., Castell D.Normal and abnormal proximal esophageal acid exposure: results of ambulatory dual-probe pH monitoring // Am. J. Gastroenterol. –1993. – Vol.88. №1 – P. 25-29.
11. El-Serag H., Sweet S., Winchester С.Update on the epidemiology of gastroesophageal reflux disease: a systematic review // Gut. – 2013. – Vol. 63– P. 871–880.
12. Fokkens W.J., Lund V.J., Mullol J. European position paper on rhinosinusitis and nasal polyps 2012 // Rhinol. Suppl. – 2012. – Vol. 3. – Р. 1–298.
13. Jenkinson C. Short form 36 (SF-36) health survey questionnaire: normative data for adults of working age // Wright. Br. Med. J. – 1993. – Vol. 306. – P. 1437–1440.
14. Katle E.J., Hart Н., Kjaergaard Т. Nose-and sinus-related quality of life and GERD // Eur. Arch. Otorhiolaringol. – 2012. –Vol. 269. № 1. –P.121–125.
15. Vakil N., Van Zanten S.V., Kahrilas Р., Jones R. Global Consensus Group the Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterol. – 2006. –Vol. 101. №8. –P.1900-1920.
16. Wasan A., Fernandez Е., N. Jamison R., Bhattacharyya N.Association of anxiety and depression with reported disease severity in patients undergoing evaluation for chronic rhinosinusitis // Ann. Otol. Rhinol. Laryngol. – 2007. –Vol. 116. №7. –P. 491-497.
17. Wiklund I.K., Junghard O., Grace E. Quality of life in the reflux and dyspepsia patients. Psychometric documentation of a new disease-specific questionnaire (QOLRAD) // Europ. J. Surg. – 1998. – Vol. 583. – P. 41–49.
Published
2018-04-17
How to Cite
ТЕМНИКОВА, Ирина Васильевна; СУББОТИНА, Мария Владимировна; ОНУЧИНА, Елена Владимировна.
Quality of life in patients with chronic rhinosinusitis associated with gastroesophageal reflux disease.
Sibirskij Medicinskij Zurnal (Irkutsk) = Siberian Medical Journal (Irkutsk) 16+, [S.l.], v. 139, n. 8, p. 33-36, apr. 2018.
ISSN 1815-7572. Available at: <http://smj.ismu.baikal.ru/index.php/osn/article/view/220>. Date accessed: 28 jan. 2026.
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Section
Original research
