INVESTIGATION OF THE OVERALL HEALTH OF WOMEN WITH STENOSING PROCESSES OF SPINAL CANAL, TAKING INTO ACCOUNT THE POSITION OF SOME OF THE INDICATORS OF THE PHYSIQUE AND LIPID METABOLISM

Abstract

Background. In developing degenerative-dystrophic spinal diseases risk factors occupy an important place. Among those, one can allocate irrecoverable factors (sex and age), and recoverable ones (hypercholesterinemia and obesity). Excess weight, as well as an increased height, also raises the probability of the spinal pathology early manifestation, and, in particular, the spinal canal degenerative stenosis. The overweight women display degenerative changes in intervertebral disks more often, than men do, and obesity facilitates developing degenerative-dystrophic changes. Obesity is closely related to disorders of lipid metabolism and metabolic syndromes. The disorders of the lipid metabolism, being a risk factor for developing vessel atherosclerosis, may facilitate degeneration of intervertebral disks through deterioration of their blood supply. Despite some known achievements, the issues of complex estimating the anthropometric and lipid indicators for the subjects with the spinal canal stenoses in coupling with the comorbidities have not been studied sufficiently, and, therefore, they do not lose their urgency. The objective of our investigation is to study anthropometric peculiarities, the lipid status, and probability of developing comorbidities with the women who suffer from the lumber spinal canal degenerative stenosis. Methods. We investigated anthropometric and lipid status of 40 women with stenosing processes of spinal canal, aged 28 to 66, who lives in Eastern Siberia region (of Irkutsk  city and Irkutsk Region). For all the subjects measured were: height, weight, waist and hips circumferences. Besides, we determined the lipid metabolism indicators in the blood serum: total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, aterogenic index and lipoprotein a. Results. Determining the body weight index with 87.5% of the investigated women testified to a weight gain, as well as to the Degree I and II obesity. 85% subjects displayed the central (abdominal) obesity, which is the basic signature of the metabolic syndrome. Decrease in the HDL cholesterol (80% cases), increase in the LDL concentration (66.7%), and the aterogenic index increase (66.6%) were the most often encountered disorders of the lipid metabolism. Simultaneously, we revealed a positive correlation between the waist/hips index and the total cholesterol increase in the blood serum. The anthropometric peculiarities and the lipid metabolism in this category of subjects testify to a a high incidence of metabolic syndrome. In turn, the anthropometric indicators correspond to increased high, and very high risk of developing comorbidities, which is necessary it must be consider determining the therapeutic approach, and developing the prevention program for patients with the lumber spine canal degenerative stenosis. Conclusions.  Thus, body build peculiarities in the interrelation with the lipid metabolism disorder indicators testify to a high probability of developing concomitant complications in women with the lumbar spinal canal stenosis. In turn, the higher frequency of metabolic disorders and characteristic anthropometric indices indicate at a high risk of developing somatopathies that require specific correction and complex prophylaxis measures.